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Fluorescence in Situ Hybridization (FISH) has revolutionized our ability to visualize the presence of chromosomal aberrations. Capabilities encompass a wide range of applications such as the detection of aneuploidy, constitutional microdeletion syndromes as well as rearrangements. These aberrations have clinical implications for numerous genetic diseases such as leukemia, lymphoma, solid tumors, autism and other developmental syndromes.
Empire Genomics is the leader in the development and manufacturing of custom labeled FISH probes, providing uniquely tailored FISH probe solutions to meet the individual needs of researchers and clinicians alike. Our FISH technology allows for fast, accurate detection and confirmation of chromosomal aberrations across the genome. Click on the product icons below to view more detailed information on each of our FISH probe options.
Empire Genomics is pleased to announce the introduction of custom labeled Fluorescence in situ Hybridization (FISH) probes.
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Our custom labeled probes offer:
- The ability to eliminate the hassle of in-house probe labeling
- Standard Nick-translational protocol
- Access to any clone in the RPCI Clone Library
- Easy validation of your aCGH Results
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- Fluorescent labels with 5 different excitation & emission profiles
- Superior sensitivity and selectivity*
- Quality tested for dye incorporation
- All probes are BAC-End Sequenced for verification
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| Check out our new FISH Probe Design Catalog |
FISH Probe Product Specifications:
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Quantity: 1ug DNA
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Number of reactions: 5
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Protocol / Instruction Guide: Click here to download
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Search by gene or region to find the BAC clone quickly & easily
Use CloneCentral to find BAC clones. After you locate your particular RPCI clone of interest, choose a dye color and add the probe to your cart - it's that simple!
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| Custom Labeled FISH Probe - Dye Colors & Specifications |
| Color | Label Description | Ex. Max | Em. Max | Ext. Coeff. |
| Aqua |
DEAC-dUTP |
431 nm |
480 nm |
50000 |
| Green |
5-Fluorescein dUTP |
496 nm |
520 nm |
85000 |
| Gold |
5(6)-Carboxyrhodamine 6G dUTP |
525 nm |
551 nm |
92000 |
| Orange |
5-TAMRA dUTP |
552 nm |
576 nm |
60000 |
| Red |
5-ROX dUTP |
580 nm |
603 nm |
75000 |
*Empire Genomics guarantees high quality probes. Based on customer specific variables such as samples tested, equipment, reagents, etc., slight protocol adjustments may be required. |