AARS-ST3GAL2 Fusion FISH Probe
The AARS-ST3GAL2 Fusion FISH Probe is used to confirm a fusion of the AARS and ST3GAL2 genes. The fusion of the AARS and ST3GAL2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AARS-ST3GAL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-RERE | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-REOR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-REGO | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-REGR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-REAQ | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-ORRE | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-OROR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-ORGO | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GORE | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GOOR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GOGO | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GOGR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GRRE | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GROR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GRGO | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GRGR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-AQRE | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-AQOR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-AQGO | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-AQGR | 20 (40 μL) | 200 μL |
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| AARS-ST3GAL2-20-AQAQ | 20 (40 μL) | 200 μL |
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AARS Gene Summary
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]
Gene Name: Alanyl-tRNA Synthetase
Chromosome: CHR16: 70286296 -70323412
Locus: 16q22.1
ST3GAL2 Gene Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. [provided by RefSeq, Jul 2008]
Gene Name: ST3 Beta-galactoside Alpha-2,3-sialyltransferase 2
Chromosome: CHR16: 70413337 -70472991
Locus: 16q22.1
Gene Diseases
The AARS ST3GAL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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