ABCA2-TRIM14 Fusion FISH Probe
The ABCA2-TRIM14 Fusion FISH Probe is used to confirm a fusion of the ABCA2 and TRIM14 genes. The fusion of the ABCA2 and TRIM14 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCA2-TRIM14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-RERE | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-REOR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-REGO | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-REGR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-OROR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GORE | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GROR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCA2-TRIM14-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCA2 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 2
Chromosome: CHR9: 139901685 -139923374
Locus: 9q34.3
TRIM14 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Gene Name: Tripartite Motif Containing 14
Chromosome: CHR9: 100831568 -100881488
Locus: 9q22.33
Gene Diseases
The ABCA2 TRIM14 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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