ABCB4-TMEM169 Fusion FISH Probe
The ABCB4-TMEM169 Fusion FISH Probe is used to confirm a fusion of the ABCB4 and TMEM169 genes. The fusion of the ABCB4 and TMEM169 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCB4-TMEM169-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-RERE | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-REOR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-REGO | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-REGR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-OROR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GORE | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GROR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCB4-TMEM169-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCB4 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily B Member 4
Chromosome: CHR7: 87031360 -87105019
Locus: 7q21.12
TMEM169 Gene Summary
The Transmembrane Protein 169 (TMEM169) gene is located on chr2 :216946588-216967506 at 2q35.
Gene Name: Transmembrane Protein 169
Chromosome: CHR2: 216946588 -216967506
Locus: 2q35
Gene Diseases
The ABCB4 TMEM169 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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