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ABCB8-NOS3 Fusion FISH Probe

The ABCB8-NOS3 Fusion FISH Probe is used to confirm a fusion of the ABCB8 and NOS3 genes. The fusion of the ABCB8 and NOS3 genes has been associated with Breast Invasive Carcinoma, and Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABCB8-NOS3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABCB8-NOS3-20-RERE 20 (40 μL) 200 μL
ABCB8-NOS3-20-REOR 20 (40 μL) 200 μL
ABCB8-NOS3-20-REGO 20 (40 μL) 200 μL
ABCB8-NOS3-20-REGR 20 (40 μL) 200 μL
ABCB8-NOS3-20-REAQ 20 (40 μL) 200 μL
ABCB8-NOS3-20-ORRE 20 (40 μL) 200 μL
ABCB8-NOS3-20-OROR 20 (40 μL) 200 μL
ABCB8-NOS3-20-ORGO 20 (40 μL) 200 μL
ABCB8-NOS3-20-ORAQ 20 (40 μL) 200 μL
ABCB8-NOS3-20-GORE 20 (40 μL) 200 μL
ABCB8-NOS3-20-GOOR 20 (40 μL) 200 μL
ABCB8-NOS3-20-GOGO 20 (40 μL) 200 μL
ABCB8-NOS3-20-GOGR 20 (40 μL) 200 μL
ABCB8-NOS3-20-GOAQ 20 (40 μL) 200 μL
ABCB8-NOS3-20-GRRE 20 (40 μL) 200 μL
ABCB8-NOS3-20-GROR 20 (40 μL) 200 μL
ABCB8-NOS3-20-GRGO 20 (40 μL) 200 μL
ABCB8-NOS3-20-GRGR 20 (40 μL) 200 μL
ABCB8-NOS3-20-GRAQ 20 (40 μL) 200 μL
ABCB8-NOS3-20-AQRE 20 (40 μL) 200 μL
ABCB8-NOS3-20-AQOR 20 (40 μL) 200 μL
ABCB8-NOS3-20-AQGO 20 (40 μL) 200 μL
ABCB8-NOS3-20-AQGR 20 (40 μL) 200 μL
ABCB8-NOS3-20-AQAQ 20 (40 μL) 200 μL

NOS3 Gene Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Gene Name: Nitric Oxide Synthase 3

Chromosome: CHR7: 150688143 -150711687

Locus: 7q36.1

ABCB8 Gene Summary

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Gene Name: ATP Binding Cassette Subfamily B Member 8

Chromosome: CHR7: 150725509 -150744869

Locus: 7q36.1

Gene Diseases

The ABCB8 NOS3 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.