SEARCH OUR PRODUCT CATALOG

ABCC2-CTNNA3 Fusion FISH Probe

The ABCC2-CTNNA3 Fusion FISH Probe is used to confirm a fusion of the ABCC2 and CTNNA3 genes. The fusion of the ABCC2 and CTNNA3 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABCC2-CTNNA3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-RERE 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-REOR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-REGO 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-REGR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-REAQ 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-ORRE 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-OROR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-ORGO 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-ORAQ 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GORE 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GOOR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GOGO 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GOGR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GOAQ 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GRRE 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GROR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GRGO 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GRGR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-GRAQ 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-AQRE 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-AQOR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-AQGO 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-AQGR 20 (40 μL) 200 μL
ABCC2-CTNNA3-20-AQAQ 20 (40 μL) 200 μL

ABCC2 Gene Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]

Gene Name: ATP Binding Cassette Subfamily C Member 2

Chromosome: CHR10: 101542462 -101611662

Locus: 10q24.2

CTNNA3 Gene Summary

This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Gene Name: Catenin Alpha 3

Chromosome: CHR10: 67679724 -69455949

Locus: 10q21.3

Gene Diseases

The ABCC2 CTNNA3 Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.