ABCC3-XYLT2 Fusion FISH Probe
The ABCC3-XYLT2 Fusion FISH Probe is used to confirm a fusion of the ABCC3 and XYLT2 genes. The fusion of the ABCC3 and XYLT2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABCC3-XYLT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ABCC3-XYLT2-20-AQAQ | 20 (40 μL) | 200 μL |
|
ABCC3 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily C Member 3
Chromosome: CHR17: 48712217 -48769063
Locus: 17q21.33
XYLT2 Gene Summary
The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Gene Name: Xylosyltransferase 2
Chromosome: CHR17: 48423392 -48438512
Locus: 17q21.33
Gene Diseases
The ABCC3 XYLT2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|