ABCC4-UGGT2 Fusion FISH Probe
The ABCC4-UGGT2 Fusion FISH Probe is used to confirm a fusion of the ABCC4 and UGGT2 genes. The fusion of the ABCC4 and UGGT2 genes has been associated with Bladder Urothelial Carcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCC4-UGGT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-RERE | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-REOR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-REGO | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-REGR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-OROR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GORE | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GROR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCC4-UGGT2-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCC4 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Name: ATP Binding Cassette Subfamily C Member 4
Chromosome: CHR13: 95672082 -95953687
Locus: 13q32.1
UGGT2 Gene Summary
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
Gene Name: UDP-glucose Glycoprotein Glucosyltransferase 2
Chromosome: CHR13: 96453835 -96705736
Locus: 13q32.1
Gene Diseases
The ABCC4 UGGT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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