ABHD12-PPP2R2A Fusion FISH Probe
The ABHD12-PPP2R2A Fusion FISH Probe is used to confirm a fusion of the ABHD12 and PPP2R2A genes. The fusion of the ABHD12 and PPP2R2A genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABHD12-PPP2R2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-RERE | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-REOR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-REGO | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-REGR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-REAQ | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-ORRE | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-OROR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-ORGO | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GORE | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GOOR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GOGO | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GOGR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GRRE | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GROR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GRGO | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GRGR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-AQRE | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-AQOR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-AQGO | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-AQGR | 20 (40 μL) | 200 μL |
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| ABHD12-PPP2R2A-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R2A Gene Summary
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Name: Protein Phosphatase 2 Regulatory Subunit Balpha
Chromosome: CHR8: 26149006 -26230195
Locus: 8p21.2
ABHD12 Gene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
Gene Name: Abhydrolase Domain Containing 12
Chromosome: CHR20: 25275378 -25371618
Locus: 20p11.21
Gene Diseases
The ABHD12 PPP2R2A Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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