ABHD2-BIRC6 Fusion FISH Probe
The ABHD2-BIRC6 Fusion FISH Probe is used to confirm a fusion of the ABHD2 and BIRC6 genes. The fusion of the ABHD2 and BIRC6 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABHD2-BIRC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-RERE | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-REOR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-REGO | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-REGR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-REAQ | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-ORRE | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-OROR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-ORGO | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GORE | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GOOR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GOGO | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GOGR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GRRE | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GROR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GRGO | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GRGR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-AQRE | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-AQOR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-AQGO | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-AQGR | 20 (40 μL) | 200 μL |
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| ABHD2-BIRC6-20-AQAQ | 20 (40 μL) | 200 μL |
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ABHD2 Gene Summary
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jan 2017]
Gene Name: Abhydrolase Domain Containing 2
Chromosome: CHR15: 89631380 -89745591
Locus: 15q26.1
BIRC6 Gene Summary
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Baculoviral IAP Repeat Containing 6
Chromosome: CHR2: 32582095 -32843965
Locus: 2p22.3
Gene Diseases
The ABHD2 BIRC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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