ALPL FISH Probe
The ALPL FISH probe is designed to hybridize to the ALPL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALPL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALPL-20-RE | 20 (40 μL) | 200 μL |  |
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| ALPL-20-GO | 20 (40 μL) | 200 μL |  |
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| ALPL-20-GR | 20 (40 μL) | 200 μL |  |
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| ALPL-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALPL-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALPL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: ALPL
Gene Name: Alkaline Phosphatase, Liver/bone/kidney
Chromosome: CHR1: 21835857-21904905
Locus: 1p36.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALPL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALPL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping