APBB1 FISH Probe
The APBB1 FISH probe is designed to hybridize to the APBB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APBB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| APBB1-20-RE | 20 (40 μL) | 200 μL |  |
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| APBB1-20-GO | 20 (40 μL) | 200 μL |  |
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| APBB1-20-GR | 20 (40 μL) | 200 μL |  |
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| APBB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| APBB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| APBB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: APBB1
Gene Name: Amyloid Beta Precursor Protein Binding Family B Member 1
Chromosome: CHR11: 6416354-6440644
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APBB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APBB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping