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AXIN2 FISH Probe

The AXIN2 FISH probe is designed to hybridize to the AXIN2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AXIN2-20-OR  (Standard Design) 20 (40 μL) 200 μL
AXIN2-20-RE 20 (40 μL) 200 μL
AXIN2-20-GO 20 (40 μL) 200 μL
AXIN2-20-GR 20 (40 μL) 200 μL
AXIN2-20-AQ 20 (40 μL) 200 μL
AXIN2-20-DIG 20 (40 μL) 200 μL
AXIN2-20-BIO 20 (40 μL) 200 μL

Gene Summary

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: AXIN2

Gene Name: Axin 2

Chromosome: CHR17: 63524682-63557740

Locus: 17q24.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: AXIN2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: AXIN2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping