BAG4 FISH Probe
The BAG4 FISH probe is designed to hybridize to the BAG4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BAG4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BAG4-20-RE | 20 (40 μL) | 200 μL |  |
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| BAG4-20-GO | 20 (40 μL) | 200 μL |  |
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| BAG4-20-GR | 20 (40 μL) | 200 μL |  |
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| BAG4-20-AQ | 20 (40 μL) | 200 μL |  |
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| BAG4-20-DIG | 20 (40 μL) | 200 μL |  |
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| BAG4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Gene Details
Gene Symbol: BAG4
Gene Name: BCL2 Associated Athanogene 4
Chromosome: CHR8: 38034105-38070819
Locus: 8p11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BAG4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BAG4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping