BCL2L10 FISH Probe
The BCL2L10 FISH probe is designed to hybridize to the BCL2L10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCL2L10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BCL2L10-20-RE | 20 (40 μL) | 200 μL |  |
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| BCL2L10-20-GO | 20 (40 μL) | 200 μL |  |
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| BCL2L10-20-GR | 20 (40 μL) | 200 μL |  |
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| BCL2L10-20-AQ | 20 (40 μL) | 200 μL |  |
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| BCL2L10-20-DIG | 20 (40 μL) | 200 μL |  |
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| BCL2L10-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: BCL2L10
Gene Name: BCL2 Like 10
Chromosome: CHR15: 52401821-52404972
Locus: 15q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BCL2L10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCL2L10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping