CAPN6 FISH Probe
The CAPN6 FISH probe is designed to hybridize to the CAPN6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAPN6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CAPN6-20-RE | 20 (40 μL) | 200 μL |  |
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| CAPN6-20-GO | 20 (40 μL) | 200 μL |  |
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| CAPN6-20-GR | 20 (40 μL) | 200 μL |  |
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| CAPN6-20-AQ | 20 (40 μL) | 200 μL |  |
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| CAPN6-20-DIG | 20 (40 μL) | 200 μL |  |
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| CAPN6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: CAPN6
Gene Name: Calpain 6
Chromosome: CHRX: 110488326-110513774
Locus: Xq23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CAPN6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CAPN6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping