CDK2AP1 FISH Probe
The CDK2AP1 FISH probe is designed to hybridize to the CDK2AP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDK2AP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDK2AP1-20-RE | 20 (40 μL) | 200 μL |  |
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| CDK2AP1-20-GO | 20 (40 μL) | 200 μL |  |
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| CDK2AP1-20-GR | 20 (40 μL) | 200 μL |  |
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| CDK2AP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDK2AP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDK2AP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: CDK2AP1
Gene Name: Cyclin Dependent Kinase 2 Associated Protein 1
Chromosome: CHR12: 123745539-123756687
Locus: 12q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDK2AP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDK2AP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping