CDKN1B FISH Probe
The CDKN1B FISH probe is designed to hybridize to the CDKN1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDKN1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDKN1B-20-RE | 20 (40 μL) | 200 μL |  |
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| CDKN1B-20-GO | 20 (40 μL) | 200 μL |  |
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| CDKN1B-20-GR | 20 (40 μL) | 200 μL |  |
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| CDKN1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDKN1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDKN1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: CDKN1B
Gene Name: Cyclin Dependent Kinase Inhibitor 1B
Chromosome: CHR12: 12870301-12875305
Locus: 12p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDKN1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDKN1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping