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CENPL FISH Probe

The CENPL FISH probe is designed to hybridize to the CENPL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
DDHD1-20-OR  (Standard Design) 20 (40 μL) 200 μL
DDHD1-20-RE 20 (40 μL) 200 μL
DDHD1-20-GO 20 (40 μL) 200 μL
DDHD1-20-GR 20 (40 μL) 200 μL
DDHD1-20-AQ 20 (40 μL) 200 μL
DDHD1-20-DIG 20 (40 μL) 200 μL
DDHD1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

Gene Details

Gene Symbol: DDHD1

Gene Name: DDHD Domain Containing 1

Chromosome: CHR14: 53503457-53620046

Locus: 14q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CENPL FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DDHD1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping