CHRNA2 FISH Probe
The CHRNA2 FISH probe is designed to hybridize to the CHRNA2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHRNA2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CHRNA2-20-RE | 20 (40 μL) | 200 μL |  |
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| CHRNA2-20-GO | 20 (40 μL) | 200 μL |  |
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| CHRNA2-20-GR | 20 (40 μL) | 200 μL |  |
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| CHRNA2-20-AQ | 20 (40 μL) | 200 μL |  |
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| CHRNA2-20-DIG | 20 (40 μL) | 200 μL |  |
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| CHRNA2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: CHRNA2
Gene Name: Cholinergic Receptor Nicotinic Alpha 2 Subunit
Chromosome: CHR8: 27317277-27336813
Locus: 8p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHRNA2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHRNA2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping