CLPB FISH Probe
The CLPB FISH probe is designed to hybridize to the CLPB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLPB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CLPB-20-RE | 20 (40 μL) | 200 μL |  |
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| CLPB-20-GO | 20 (40 μL) | 200 μL |  |
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| CLPB-20-GR | 20 (40 μL) | 200 μL |  |
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| CLPB-20-AQ | 20 (40 μL) | 200 μL |  |
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| CLPB-20-DIG | 20 (40 μL) | 200 μL |  |
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| CLPB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: CLPB
Gene Name: ClpB Homolog, Mitochondrial AAA ATPase Chaperonin
Chromosome: CHR11: 72003469-72145568
Locus: 11q13.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLPB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CLPB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping