COCH FISH Probe
The COCH FISH probe is designed to hybridize to the COCH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COCH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COCH-20-RE | 20 (40 μL) | 200 μL |  |
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| COCH-20-GO | 20 (40 μL) | 200 μL |  |
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| COCH-20-GR | 20 (40 μL) | 200 μL |  |
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| COCH-20-AQ | 20 (40 μL) | 200 μL |  |
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| COCH-20-DIG | 20 (40 μL) | 200 μL |  |
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| COCH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: COCH
Gene Name: Cochlin
Chromosome: CHR14: 31343740-31359822
Locus: 14q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COCH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COCH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping