COL11A2 FISH Probe
The COL11A2 FISH probe is designed to hybridize to the COL11A2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COL11A2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COL11A2-20-RE | 20 (40 μL) | 200 μL |  |
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| COL11A2-20-GO | 20 (40 μL) | 200 μL |  |
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| COL11A2-20-GR | 20 (40 μL) | 200 μL |  |
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| COL11A2-20-AQ | 20 (40 μL) | 200 μL |  |
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| COL11A2-20-DIG | 20 (40 μL) | 200 μL |  |
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| COL11A2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq, Jul 2009]
Gene Details
Gene Symbol: COL11A2
Gene Name: Collagen Type XI Alpha 2 Chain
Chromosome: CHR6_dbb_hap3: 4411775-4441552
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COL11A2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COL11A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping