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COQ3 FISH Probe

The COQ3 FISH probe is designed to hybridize to the COQ3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
COQ3-20-OR  (Standard Design) 20 (40 μL) 200 μL
COQ3-20-RE 20 (40 μL) 200 μL
COQ3-20-GO 20 (40 μL) 200 μL
COQ3-20-GR 20 (40 μL) 200 μL
COQ3-20-AQ 20 (40 μL) 200 μL
COQ3-20-DIG 20 (40 μL) 200 μL
COQ3-20-BIO 20 (40 μL) 200 μL

Gene Summary

Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

Gene Details

Gene Symbol: COQ3

Gene Name: Coenzyme Q3, Methyltransferase

Chromosome: CHR6: 99817347-99842082

Locus: 6q16.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: COQ3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: COQ3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping