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CYP27B1 FISH Probe

The CYP27B1 FISH probe is designed to hybridize to the CYP27B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CYP27B1-20-OR  (Standard Design) 20 (40 μL) 200 μL
CYP27B1-20-RE 20 (40 μL) 200 μL
CYP27B1-20-GO 20 (40 μL) 200 μL
CYP27B1-20-GR 20 (40 μL) 200 μL
CYP27B1-20-AQ 20 (40 μL) 200 μL
CYP27B1-20-DIG 20 (40 μL) 200 μL
CYP27B1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CYP27B1

Gene Name: Cytochrome P450 Family 27 Subfamily B Member 1

Chromosome: CHR12: 58156116-58160976

Locus: 12q14.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CYP27B1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CYP27B1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping