DDHD1 FISH Probe
The DDHD1 FISH probe is designed to hybridize to the DDHD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DDHD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DDHD1-20-RE | 20 (40 μL) | 200 μL |  |
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| DDHD1-20-GO | 20 (40 μL) | 200 μL |  |
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| DDHD1-20-GR | 20 (40 μL) | 200 μL |  |
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| DDHD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DDHD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DDHD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: DDHD1
Gene Name: DDHD Domain Containing 1
Chromosome: CHR14: 53503457-53620046
Locus: 14q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DDHD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DDHD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping