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DENND1B FISH Probe

The DENND1B FISH probe is designed to hybridize to the DENND1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
DENND1B-20-OR  (Standard Design) 20 (40 μL) 200 μL
DENND1B-20-OR 20 (40 μL) 200 μL
DENND1B-20-OR 20 (40 μL) 200 μL
DENND1B-20-OR 20 (40 μL) 200 μL
DENND1B-20-OR 20 (40 μL) 200 μL
DENND1B-20-OR 20 (40 μL) 200 μL
DENND1B-20-OR 20 (40 μL) 200 μL

Gene Summary

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

Gene Details

Gene Symbol: DENND1B

Gene Name: DENN Domain Containing 1B

Chromosome: CHR1: 197473878-197744623

Locus: 1q31.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DENND1B FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DENND1B-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping