DPPA4 FISH Probe
The DPPA4 FISH probe is designed to hybridize to the DPPA4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPPA4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| DPPA4-20-RE | 20 (40 μL) | 200 μL |  |
|
| DPPA4-20-GO | 20 (40 μL) | 200 μL |  |
|
| DPPA4-20-GR | 20 (40 μL) | 200 μL |  |
|
| DPPA4-20-AQ | 20 (40 μL) | 200 μL |  |
|
| DPPA4-20-DIG | 20 (40 μL) | 200 μL |  |
|
| DPPA4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Details
Gene Symbol: DPPA4
Gene Name: Developmental Pluripotency Associated 4
Chromosome: CHR3: 109044987-109056419
Locus: 3q13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DPPA4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DPPA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping