EFNB3 FISH Probe
The EFNB3 FISH probe is designed to hybridize to the EFNB3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EFNB3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EFNB3-20-RE | 20 (40 μL) | 200 μL |  |
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| EFNB3-20-GO | 20 (40 μL) | 200 μL |  |
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| EFNB3-20-GR | 20 (40 μL) | 200 μL |  |
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| EFNB3-20-AQ | 20 (40 μL) | 200 μL |  |
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| EFNB3-20-DIG | 20 (40 μL) | 200 μL |  |
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| EFNB3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EFNB3
Gene Name: Ephrin B3
Chromosome: CHR17: 7608519-7614693
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EFNB3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EFNB3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping