FAM111B FISH Probe
The FAM111B FISH probe is designed to hybridize to the FAM111B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FAM111B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FAM111B-20-RE | 20 (40 μL) | 200 μL |  |
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| FAM111B-20-GO | 20 (40 μL) | 200 μL |  |
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| FAM111B-20-GR | 20 (40 μL) | 200 μL |  |
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| FAM111B-20-AQ | 20 (40 μL) | 200 μL |  |
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| FAM111B-20-DIG | 20 (40 μL) | 200 μL |  |
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| FAM111B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: FAM111B
Gene Name: Family With Sequence Similarity 111 Member B
Chromosome: CHR11: 58874657-58894888
Locus: 11q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FAM111B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FAM111B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping