FBN1 FISH Probe
The FBN1 FISH probe is designed to hybridize to the FBN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FBN1-20-RE | 20 (40 μL) | 200 μL |  |
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| FBN1-20-GO | 20 (40 μL) | 200 μL |  |
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| FBN1-20-GR | 20 (40 μL) | 200 μL |  |
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| FBN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| FBN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| FBN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: FBN1
Gene Name: Fibrillin 1
Chromosome: CHR15: 48700502-48937985
Locus: 15q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FBN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FBN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping