FGD4 FISH Probe
The FGD4 FISH probe is designed to hybridize to the FGD4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FGD4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FGD4-20-RE | 20 (40 μL) | 200 μL |  |
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| FGD4-20-GO | 20 (40 μL) | 200 μL |  |
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| FGD4-20-GR | 20 (40 μL) | 200 μL |  |
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| FGD4-20-AQ | 20 (40 μL) | 200 μL |  |
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| FGD4-20-DIG | 20 (40 μL) | 200 μL |  |
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| FGD4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: FGD4
Gene Name: FYVE, RhoGEF And PH Domain Containing 4
Chromosome: CHR12: 32655040-32798984
Locus: 12p11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FGD4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FGD4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping