FUBP1 FISH Probe
The FUBP1 FISH probe is designed to hybridize to the FUBP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FUBP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| FUBP1-20-RE | 20 (40 μL) | 200 μL |  |
|
| FUBP1-20-GO | 20 (40 μL) | 200 μL |  |
|
| FUBP1-20-GR | 20 (40 μL) | 200 μL |  |
|
| FUBP1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| FUBP1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| FUBP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: FUBP1
Gene Name: Far Upstream Element Binding Protein 1
Chromosome: CHR1: 78413590-78444777
Locus: 1p31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: FUBP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FUBP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping