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GABA FISH Probe

The GABA FISH probe is designed to hybridize to the GABA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABAT-20-OR  (Standard Design) 20 (40 μL) 200 μL
ABAT-20-RE 20 (40 μL) 200 μL
ABAT-20-GO 20 (40 μL) 200 μL
ABAT-20-GR 20 (40 μL) 200 μL
ABAT-20-AQ 20 (40 μL) 200 μL
ABAT-20-DIG 20 (40 μL) 200 μL
ABAT-20-BIO 20 (40 μL) 200 μL

Gene Summary

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ABAT

Gene Name: 4-aminobutyrate Aminotransferase

Chromosome: CHR16: 8768443-8878432

Locus: 16p13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GABA FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ABAT-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping