SEARCH OUR PRODUCT CATALOG

As of February 28th, Empire is operating as an essential New York State business and has no production or shipping delays

GAS5 FISH Probe

The GAS5 FISH probe is designed to hybridize to the GAS5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
GAS5-20-OR  (Standard Design) 20 (40 μL) 200 μL
GAS5-20-RE 20 (40 μL) 200 μL
GAS5-20-GO 20 (40 μL) 200 μL
GAS5-20-GR 20 (40 μL) 200 μL
GAS5-20-AQ 20 (40 μL) 200 μL
GAS5-20-DIG 20 (40 μL) 200 μL
GAS5-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene produces a spliced long non-coding RNA and is a member of the 5' terminal oligo-pyrimidine class of genes. It is a small nucleolar RNA host gene, containing multiple C/D box snoRNA genes in its introns. Part of the secondary RNA structure of the encoded transcript mimics glucocorticoid response element (GRE) which means it can bind to the DNA binding domain of the glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1). This action blocks the glucocorticoid receptor from being activated and thereby stops it from regulating the transcription of its target genes. This transcript is also thought to regulate the transcriptional activity of other receptors, such as androgen, progesterone and mineralocorticoid receptors, that can bind to its GRE mimic region. Multiple functions have been associated with this transcript, including cellular growth arrest and apoptosis. It has also been identified as a potential tumor suppressor, with its down-regulation associated with cancer in multiple different tissues. [provided by RefSeq, Mar 2015]

Gene Details

Gene Symbol: GAS5

Gene Name: Growth Arrest Specific 5 (non-protein Coding)

Chromosome: CHR1: 173833038-173837125

Locus: 1q25.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GAS5 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GAS5-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping