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GCLC FISH Probe

The GCLC FISH probe is designed to hybridize to the GCLC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GCLC-20-OR  (Standard Design) 20 (40 μL) 200 μL
GCLC-20-RE 20 (40 μL) 200 μL
GCLC-20-GO 20 (40 μL) 200 μL
GCLC-20-GR 20 (40 μL) 200 μL
GCLC-20-AQ 20 (40 μL) 200 μL
GCLC-20-DIG 20 (40 μL) 200 μL
GCLC-20-BIO 20 (40 μL) 200 μL

Gene Summary

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]

Gene Details

Gene Symbol: GCLC

Gene Name: Glutamate-cysteine Ligase Catalytic Subunit

Chromosome: CHR6: 53362139-53409927

Locus: 6p12.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GCLC FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GCLC-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping