GHRL FISH Probe
The GHRL FISH probe is designed to hybridize to the GHRL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GHRL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GHRL-20-RE | 20 (40 μL) | 200 μL |  |
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| GHRL-20-GO | 20 (40 μL) | 200 μL |  |
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| GHRL-20-GR | 20 (40 μL) | 200 μL |  |
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| GHRL-20-AQ | 20 (40 μL) | 200 μL |  |
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| GHRL-20-DIG | 20 (40 μL) | 200 μL |  |
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| GHRL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: GHRL
Gene Name: Ghrelin And Obestatin Prepropeptide
Chromosome: CHR3: 10327433-10334631
Locus: 3p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GHRL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GHRL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping