GLDC FISH Probe
The GLDC FISH probe is designed to hybridize to the GLDC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLDC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GLDC-20-RE | 20 (40 μL) | 200 μL |  |
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| GLDC-20-GO | 20 (40 μL) | 200 μL |  |
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| GLDC-20-GR | 20 (40 μL) | 200 μL |  |
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| GLDC-20-AQ | 20 (40 μL) | 200 μL |  |
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| GLDC-20-DIG | 20 (40 μL) | 200 μL |  |
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| GLDC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: GLDC
Gene Name: Glycine Decarboxylase
Chromosome: CHR9: 6532463-6645692
Locus: 9p24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GLDC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GLDC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping