GLE1 FISH Probe
The GLE1 FISH probe is designed to hybridize to the GLE1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLE1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| GLE1-20-RE | 20 (40 μL) | 200 μL |  |
|
| GLE1-20-GO | 20 (40 μL) | 200 μL |  |
|
| GLE1-20-GR | 20 (40 μL) | 200 μL |  |
|
| GLE1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| GLE1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| GLE1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GLE1
Gene Name: GLE1, RNA Export Mediator
Chromosome: CHR9: 131266970-131304580
Locus: 9q34.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GLE1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GLE1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping