GSTA2 FISH Probe
The GSTA2 FISH probe is designed to hybridize to the GSTA2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GSTA2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GSTA2-20-RE | 20 (40 μL) | 200 μL |  |
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| GSTA2-20-GO | 20 (40 μL) | 200 μL |  |
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| GSTA2-20-GR | 20 (40 μL) | 200 μL |  |
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| GSTA2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GSTA2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GSTA2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GSTA2
Gene Name: Glutathione S-transferase Alpha 2
Chromosome: CHR6: 52614884-52628361
Locus: 6p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GSTA2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GSTA2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping