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HLA-DQB2 FISH Probe

The HLA-DQB2 FISH probe is designed to hybridize to the HLA-DQB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
HLA-DQB2-20-OR  (Standard Design) 20 (40 μL) 200 μL
HLA-DQB2-20-RE 20 (40 μL) 200 μL
HLA-DQB2-20-GO 20 (40 μL) 200 μL
HLA-DQB2-20-GR 20 (40 μL) 200 μL
HLA-DQB2-20-AQ 20 (40 μL) 200 μL
HLA-DQB2-20-DIG 20 (40 μL) 200 μL
HLA-DQB2-20-BIO 20 (40 μL) 200 μL

Gene Summary

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010]

Gene Details

Gene Symbol: HLA-DQB2

Gene Name: Major Histocompatibility Complex, Class II, DQ Beta 2

Chromosome: CHR6_qbl_hap6: 3955994-3963453

Locus: 6p21.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: HLA-DQB2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: HLA-DQB2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping