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IL12RB2 FISH Probe

The IL12RB2 FISH probe is designed to hybridize to the IL12RB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
IL12RB2-20-OR  (Standard Design) 20 (40 μL) 200 μL
IL12RB2-20-RE 20 (40 μL) 200 μL
IL12RB2-20-GO 20 (40 μL) 200 μL
IL12RB2-20-GR 20 (40 μL) 200 μL
IL12RB2-20-AQ 20 (40 μL) 200 μL
IL12RB2-20-DIG 20 (40 μL) 200 μL
IL12RB2-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]

Gene Details

Gene Symbol: IL12RB2

Gene Name: Interleukin 12 Receptor Subunit Beta 2

Chromosome: CHR1: 67773046-67862583

Locus: 1p31.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: IL12RB2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: IL12RB2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping