IRF4 FISH Probe
The IRF4 FISH probe is designed to hybridize to the IRF4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IRF4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IRF4-20-RE | 20 (40 μL) | 200 μL |  |
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| IRF4-20-GO | 20 (40 μL) | 200 μL |  |
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| IRF4-20-GR | 20 (40 μL) | 200 μL |  |
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| IRF4-20-AQ | 20 (40 μL) | 200 μL |  |
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| IRF4-20-DIG | 20 (40 μL) | 200 μL |  |
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| IRF4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: IRF4
Gene Name: Interferon Regulatory Factor 4
Chromosome: CHR6: 391738-411443
Locus: 6p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IRF4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IRF4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping