KDM6B FISH Probe
The KDM6B FISH probe is designed to hybridize to the KDM6B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KDM6B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KDM6B-20-RE | 20 (40 μL) | 200 μL |  |
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| KDM6B-20-GO | 20 (40 μL) | 200 μL |  |
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| KDM6B-20-GR | 20 (40 μL) | 200 μL |  |
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| KDM6B-20-AQ | 20 (40 μL) | 200 μL |  |
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| KDM6B-20-DIG | 20 (40 μL) | 200 μL |  |
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| KDM6B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Details
Gene Symbol: KDM6B
Gene Name: Lysine Demethylase 6B
Chromosome: CHR17: 7743234-7758118
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KDM6B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KDM6B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping