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KLHL3 FISH Probe

The KLHL3 FISH probe is designed to hybridize to the KLHL3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
KLHL3-20-OR  (Standard Design) 20 (40 μL) 200 μL
KLHL3-20-RE 20 (40 μL) 200 μL
KLHL3-20-GO 20 (40 μL) 200 μL
KLHL3-20-GR 20 (40 μL) 200 μL
KLHL3-20-AQ 20 (40 μL) 200 μL
KLHL3-20-DIG 20 (40 μL) 200 μL
KLHL3-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]

Gene Details

Gene Symbol: KLHL3

Gene Name: Kelch Like Family Member 3

Chromosome: CHR5: 136953188-137071779

Locus: 5q31.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: KLHL3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KLHL3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping