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KMT2A FISH Probe

The KMT2A FISH probe is designed to hybridize to the KMT2A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KMT2A-20-OR  (Standard Design) 20 (40 μL) 200 μL
KMT2A-20-RE 20 (40 μL) 200 μL
KMT2A-20-GO 20 (40 μL) 200 μL
KMT2A-20-GR 20 (40 μL) 200 μL
KMT2A-20-AQ 20 (40 μL) 200 μL
KMT2A-20-DIG 20 (40 μL) 200 μL
KMT2A-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]

Gene Details

Gene Symbol: KMT2A

Gene Name: Lysine Methyltransferase 2A

Chromosome: CHR11: 118436489-118526831

Locus: 11q23.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: KMT2A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KMT2A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping