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LEPR FISH Probe

The LEPR FISH probe is designed to hybridize to the LEPR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
LEPR-20-OR  (Standard Design) 20 (40 μL) 200 μL
LEPR-20-RE 20 (40 μL) 200 μL
LEPR-20-GO 20 (40 μL) 200 μL
LEPR-20-GR 20 (40 μL) 200 μL
LEPR-20-AQ 20 (40 μL) 200 μL
LEPR-20-DIG 20 (40 μL) 200 μL
LEPR-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]

Gene Details

Gene Symbol: LEPR

Gene Name: Leptin Receptor

Chromosome: CHR1: 65886334-66103176

Locus: 1p31.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: LEPR FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: LEPR-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping