MBD3 FISH Probe
The MBD3 FISH probe is designed to hybridize to the MBD3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MBD3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MBD3-20-RE | 20 (40 μL) | 200 μL |  |
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| MBD3-20-GO | 20 (40 μL) | 200 μL |  |
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| MBD3-20-GR | 20 (40 μL) | 200 μL |  |
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| MBD3-20-AQ | 20 (40 μL) | 200 μL |  |
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| MBD3-20-DIG | 20 (40 μL) | 200 μL |  |
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| MBD3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: MBD3
Gene Name: Methyl-CpG Binding Domain Protein 3
Chromosome: CHR19: 1576677-1592652
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MBD3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MBD3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping