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MRE11 FISH Probe

The MRE11 FISH probe is designed to hybridize to the MRE11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
MRE11-20-OR  (Standard Design) 20 (40 μL) 200 μL
MRE11-20-RE 20 (40 μL) 200 μL
MRE11-20-GO 20 (40 μL) 200 μL
MRE11-20-GR 20 (40 μL) 200 μL
MRE11-20-AQ 20 (40 μL) 200 μL
MRE11-20-DIG 20 (40 μL) 200 μL
MRE11-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: MRE11

Gene Name: MRE11 Homolog, Double Strand Break Repair Nuclease

Chromosome: CHR11: 94512700-94415569

Locus: 11q21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MRE11 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MRE11-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping