NKX2-8 FISH Probe
The NKX2-8 FISH probe is designed to hybridize to the NKX2-8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NKX2-8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NKX2-8-20-RE | 20 (40 μL) | 200 μL |  |
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| NKX2-8-20-GO | 20 (40 μL) | 200 μL |  |
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| NKX2-8-20-GR | 20 (40 μL) | 200 μL |  |
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| NKX2-8-20-AQ | 20 (40 μL) | 200 μL |  |
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| NKX2-8-20-DIG | 20 (40 μL) | 200 μL |  |
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| NKX2-8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: NKX2-8
Gene Name: NK2 Homeobox 8
Chromosome: CHR14: 37049215-37051786
Locus: 14q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NKX2-8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NKX2-8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping